Management of Supratentorial Central Neurocytomas in Children

Initial Management At Presentation

  • Surgical resection: Complete tumor resection is the procedure of choice whenever it can be accomplished. With classical neurocytomas, tumor bleeding is often the only cause of inability to achieve this aim.

Adjunctive Therapies

  • Radiation therapy: An alternative to complete tumor resection is radiotherapy.
  • Chemotherapy: Two chemotherapeutic agents have been used: MCNU(ranimustine) and CCNU(lomustine).

Follow-up

  • Initial visit at 6 months: Initially, a 6-month MRI is indicated, especially if the tumor histology is atypical or the classical neurocytoma shows a high MIB-1 labeling index.