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On The Horizon for Subependymal Giant Cell Astrocytomas in Children

  • Endoscopic management: Endoscopic approaches provide a theoretical advantage of minimally invasive access for safe extirpation of the tumor and can also provide treatment of associated hydrocephalus. More widespread use may occur in the coming years (6).
  • mTOR inhibitors: In the coming years, medical treatment (rapamycin) will certainly take a more prominent place in the management of children with TSC as the pathogenesis of SEGAs at the molecular level is better understood (11, 14, 19, 20).