Warning: Use of undefined constant _FILE_ - assumed '_FILE_' (this will throw an Error in a future version of PHP) in /home/ispn6769/public_html/wp-content/themes/ispn/functions.php on line 88

Outcome of Therapies for Metabolic Bone Disease in Children

Outcome After Surgery

  • Advanced symptoms = poor prognosis: Children with advanced neurological symptoms at the time of intervention have a worse prognosis.
  • Decompression successful for most: Craniovertebral decompression ameliorates symptoms of cervicomedullary compression (neurological and respiratory) in most children with achondroplasia (3).
  • Fusion successful for 90%: Successful fusion can be anticipated in up to 90% of children wtih skeletal dysplasia (1, 7).
  • Instability adjacent to fusion for 1/3: Junctional instability below a previous successful fusion has been reported in up to one third of children with Morquio syndrome, thereby underscoring the importance of long-term follow-up (7).