Germinal matrix hemorrhage – Germinal matrix hemorrhage – Bleeding into the periventricular germinal matrix of the brain. It is felt to be due to rupture of delicate vascular vessels within the germinal matrix resulting from hypoxic ischemic injury and death to those vessels’ cell walls. The resulting hemorrhage can then ruptures into the ventricles (germinal matrix intraventricular hemorrhage), spreading throughout the system in a variable degree.